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Phenindamine overdose
Definition:
This poisoning is from an overdose of phenindamine.

Alternative Names:
Antihistamine; Amilon; Fenaclor; Nolamine; Norphenamine; Prophamine

Poisonous Ingredient:
Phenindamine
Where Found:
  • Nolahist
  • Amilon
  • Fenaclor
  • Nolamine
  • Norphenamine
  • Prophamine
Symptoms:
Home Treatment:

Seek medical care immediately. Call Poison Control. Do not induce vomiting.
Before Calling Emergency:
Determine the following information:
  • The patient's age, weight, and condition
  • Name of product (as well as the ingredients and strength, if known)
  • The time it was swallowed
  • The amount swallowed
  • If the medication was prescribed for the patient
Poison Control, or a local emergency number:
See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.
What to expect at the emergency room:
Some or all of the following procedures may be performed:
  • For swallowed poison
    • Placement of a tube down the nose and into the stomach (a nasogastric tube, or an NG tube) to wash out the stomach (gastric lavage)
    • Activated charcoal administration
    • Endoscopy -- the placement of a camera down the throat to see the extent of burns to the esophagus and the stomach
    • Give IV fluids
    • Admission to the hospital
    • Give an antidote
    • Treat the symptoms
  • For inhaled poisons
    • A breathing tube may need to be inserted
    • Oxygen
    • Admission to the hospital or to the intensive care unit
    • Bronchoscopy (inserting a camera down the throat into the airway to evaluate the extent of burns to the airway and lungs)
  • For skin exposure
    • Irrigation (washing of the skin), perhaps every few hours for several days
    • Skin debridement (surgical removal of burned skin)
    • Admission or transfer to a hospital that specializes in burn care
Expectations (prognosis):
If the patient survives the first 24 hours, survival is likely. Few patients actually die from an antihistamine overdose.
Review Date: 2/2/2002
Reviewed By: Kevin G. Wheeler, M.D., Department of Emergency Medicine, Boston Medical Center, Boston, MA. Review provided by VeriMed Healthcare Network.
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