The open lung biopsy is done in a hospital operating room under general anesthesia. You are given a sedative by injection about 1 hour before the procedure. An intravenous (IV) line is placed in a vein, usually in the arm. Throughout the procedure, you are given a mixture of anesthetic gas and oxygen through a hollow tube that is inserted through the mouth and into the airway that leads to the lungs. The skin is cleansed and an incision is made over the area to be sampled. A small piece of the lung tissue is removed. The incision is closed with stitches. A chest tube may be left in place, with one end inside the chest cavity and the other protruding through the rib space below the incision for 1 to 2 days to prevent the lung from collapsing.
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