|
| Pronunciation |
|
 (boe
SEN
tan) |
|
|
| Brand Names |
|
| Tracleer™ |
|
|
| Therapeutic
Categories |
|
|
Endothelin Antagonist |
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|
| What key warnings should I know
about before taking this
medicine? |
|
|
This medicine may cause severe liver damage. Do not take this medicine if
you are pregnant. You cannot obtain this medicine from your pharmacy. It is
available only through the company which makes it. |
|
|
| Reasons not to take this
medicine |
|
|
If you have an allergy to bosentan or any other part of this
medicine.
Tell healthcare provider if you are allergic to any medicine. Make
sure to tell about the allergy and how it affected you. This includes telling
about rash; hives; itching; shortness of breath; wheezing; cough; swelling of
face, lips, tongue, or throat; or any other symptoms involved.
If you have liver disease.
If you are taking any of the following medicines: Cyclosporine or
glyburide.
If you are pregnant or may be pregnant.
If you are breast-feeding. |
|
|
| What is this medicine used
for? |
|
|
This medicine is used to treat increased pressure in the
lungs. |
|
|
| How does it work? |
|
|
Bosentan blocks endothelin, a chemical in the blood that causes blood
vessels to narrow. |
|
|
| How is it best taken? |
|
|
To gain the most benefit, do not miss doses.
Take this medicine with or without food. Take with food if it causes
an upset stomach. |
|
|
| What do I do if I miss a
dose? |
|
|
Take a missed dose as soon as possible.
If it is almost time for the next dose, skip the missed dose and
return to your regular schedule.
Do not take a double dose or extra doses.
Do not change dose or stop medicine. Talk with healthcare
provider. |
|
|
| What are the precautions when
taking this
medicine? |
|
|
Check medicines with healthcare provider. This medicine may not mix
well with other medicines.
Avoid grapefruit and grapefruit juice.
Avoid or limit alcohol intake (includes wine, beer, and liquor) to
less than 3 drinks a day. Drinking too much alcohol may increase the risk of
liver disease.
Birth control pills and other hormone-based birth control may not
work to prevent pregnancy. Use other forms of birth control while taking this
medicine. |
|
|
| What are the common side effects
of this
medicine? |
|
|
Headache. Mild pain medicine may help.
Liver damage can rarely occur. |
|
|
| What should I monitor? |
|
|
Change in condition being treated. Is it better, worse, or about the
same?
If you are a female of childbearing age, take a pregnancy test before
starting this medicine.
If you are a female of childbearing age, take a monthly pregnancy
test.
Check blood work (liver function, hemoglobin, hematocrit). Talk with
healthcare provider.
Follow up with healthcare provider. |
|
|
| Reasons to call healthcare
provider
immediately |
|
|
If you suspect an overdose, call your local poison control center
immediately or dial 911.
Signs of a life-threatening reaction. These include wheezing; chest
tightness; fever; itching; bad cough; blue skin color; fits; or swelling of
face, lips, tongue, or throat.
Severe belly pain.
Severe nausea or vomiting.
Not hungry.
Dark urine or yellow skin or eyes.
Feeling extremely tired or weak.
Any rash.
For females, if you become pregnant while taking this medicine.
No improvement in condition or feeling
worse. |
|
|
| How should I store this
medicine? |
|
|
Store at room temperature.
Protect from light.
Protect from moisture. Do not store in a bathroom or
kitchen. |
|
|
| General statements |
|
|
Do not share your medicine with others and do not take anyone else's
medicine.
Keep all medicine out of the reach of children and pets.
Keep a list of all your medicines (prescription, natural products,
supplements, vitamins, over-the-counter) with you. Give this list to healthcare
provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
Talk with healthcare provider before starting any new medicine,
including over-the-counter, natural products, or
vitamins. |
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