Drugs >  Diethylstilbestrol
Diethylstilbestrol
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(dye eth il stil BES trole)

Brand Names
Stilphostrol®

Foreign Brand Names
Honvol® (Canada)

Therapeutic Categories
Estrogen Derivative

Reasons not to take this medicine

  • If you have an allergy to another estrogen, diethylstilbestrol, or any other part of the medicine.
  • If you have any of the following conditions: Unexplained vaginal bleeding, breast cancer except in certain patients with widespread disease.
  • If you are pregnant or breast-feeding.


What is this medicine used for?

  • This medicine can be used to treat inoperable, progressing prostate cancer.


How does it work?

  • Diethylstilbestrol competes with testosterone to slow the growth of the cancer.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach or take as directed by your healthcare provider.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Limit alcohol intake (includes wine, beer, and liquor).
  • Do not use if you have had breast cancer.
  • Not to be taken by women.
  • Use caution if you have a weakened heart or high blood pressure. Talk with healthcare provider.
  • Tell healthcare provider if you have ever had any blood circulation problems or clots in your legs, arms, or lungs.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.


What are the common side effects of this medicine?

  • Headache. Mild pain medicine may help.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Belly pain and cramps.
  • Breast enlargement/tenderness.


What should I monitor?

  • Check blood pressure and heart rate (pulse) regularly.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe headache.
  • Severe nausea, vomiting, and/or diarrhea.
  • Swelling/pain of a leg or arm, sudden shortness of breath, difficulty breathing, chest pain.
  • A lump in the breast.
  • Any rash.


How should I store this medicine?

  • Store in a dry place at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Read the package insert for more details (given with the medicine).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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