Drugs >  Digoxin
Digoxin
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(di JOKS in)

Brand Names
Lanoxicaps®; Lanoxin®

Foreign Brand Names
Novo-Digoxin® (Canada); Mapluxin® (Mexico)

Therapeutic Categories
Antiarrhythmic Agent, Class IV; Cardiac Glycoside

Reasons not to take this medicine

  • If you have an allergy to another cardiac glycoside, digoxin, or any other part of the medicine.
  • If you have any of the following conditions: Too much of this medicine in your body, ventricular tachycardia, ventricular fibrillation, idiopathic hypertropic subaortic stenosis, constrictive pericarditis, amyloid disease, problem with the electrical system of the heart unless a pacemaker has fixed it, Wolff-Parkinson-White syndrome and atrial fibrillation.


What is this medicine used for?

  • This medicine treats hearts (congestive heart failure) by strengthening the pumping action. It is also used to slow the heart rate (pulse) in patients whose hearts are racing in a certain way (atrial fibrillation/flutter).


How does it work?

  • Digoxin strengthens the heart by increasing calcium inside the cells of the heart. The heart can pump stronger and more effectively as a result. It decreases the number of electrical impulses that drive the heart rate (pulse) and this slows the speed down.


How is it best taken?

  • Take separately from high bran fiber, otherwise, take with or without food. Take with food if this medicine causes an upset stomach.
  • Take at a similar time every day.
  • Swallow capsule whole.
  • A liquid (elixir) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
  • Do not take antacids, dietary bran fiber, sucralfate, cholestyramine, colestipol, or kaolin-pectin within 4-6 hours of this medicine.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider, particularly if you are taking amiodarone, verapamil, or quinidine.
  • Wear disease medical alert identification for heart disease.
  • If you are 65 or older, you may have more side effects.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Confusion, especially in the elderly and patients with kidney disease.
  • Anorexia, belly pain, and cramps.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea.


What should I monitor?

  • Check heart rate (pulse). Can be taken daily before taking the medicine. Ask healthcare provider to teach you how to take your pulse.
  • Check digoxin serum concentrations. Easiest to have blood drawn in the morning before daily dose (just take dose after blood drawn). Talk with healthcare provider.
  • Check blood work (potassium). Talk with healthcare provider if you are taking a water pill.
  • Watch for swelling of legs or belly, shortness of breath, weight gain, exercise tolerance. If any of these worsen, talk with healthcare provider.
  • Report a 3-5 pound weight gain if you have heart failure.
  • Follow diet plan (low sodium if heart failure patient) as recommended. Talk with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Changes in thinking clearly and logically.
  • Too tired or sleepy.
  • Passing out, fainting, dizziness, or lightheadedness.
  • Severe nausea, vomiting, and/or diarrhea.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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