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| Pronunciation |
|
 (dye
hye droe er GOT a
meen) |
|
|
| Brand Names |
|
| D.H.E. 45®;
Migranal® |
|
|
| Therapeutic
Categories |
|
|
Ergot Derivative |
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|
| What key warnings should I know
about before taking this
medicine? |
|
|
This medicine does not mix well with many medicines. Serious reactions may
occur. Check all medicines with healthcare provider. |
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|
| Reasons not to take this
medicine |
|
|
If you have an allergy to dihydroergotamine or any other part of this
medicine.
Tell healthcare provider if you are allergic to any medicine. Make
sure to tell about the allergy and how it affected you. This includes telling
about rash; hives; itching; shortness of breath; wheezing; cough; swelling of
face, lips, tongue, or throat; or any other symptoms involved.
If you have any of the following conditions: Heart disease, kidney
disease, liver disease, poor intestinal blood flow, or uncontrolled high blood
pressure.
If you have a severe infection.
If you are taking any of these medicines: Amprenavir, clarithromycin,
erythromycin, indinavir,itraconazole, ketoconazole, nelfinavir, ritonavir, or
troleandomycin.
If you have taken isocarboxazid, phenelzine, or tranylcypromine in
the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine,
and tranylcypromine) must be stopped 14 days before this medicine is started.
Taking the two together could cause dangerously high blood pressure.
If you have taken almotriptan, frovatriptan, naratriptan,
rizatriptan, sumatriptan, or zolmitriptan in the last 24 hours.
If you have taken ergotamine or methysergide in the last 24 hours.
If you are pregnant or may be pregnant.
If you are breast-feeding. |
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|
| What is this medicine used
for? |
|
|
This medicine is used to treat migraine
headaches. |
|
|
| How does it work? |
|
|
Ergotamine squeezes certain blood vessels in the brain preventing
irritation and inflammation. |
|
|
| How is it best taken? |
|
|
Injection:
This medicine is given as a shot into a muscle, vein, or into the
fatty part of the skin.
Your healthcare provider may teach you how to give the shot.
Wash your hands before and after use.
Throw away needles in needle/sharp disposal box and return box to
healthcare provider when full.
If you get another attack the same day, do not use unless at least 6
hours have passed since your last shot.
Inhalation:
For inhaling through the nostrils. Prime pump by squeezing it 4
times. Inhale 1 spray in each nostril. Wait 15 minutes. Inhale another spray in
each nostril. |
|
|
| What do I do if I miss a
dose? |
|
|
This medicine is taken on an as needed
basis. |
|
|
| What are the precautions when
taking this
medicine? |
|
|
Check medicines with healthcare provider. This medicine may not mix
well with other medicines.
Avoid cigarette smoking.
Use caution if you have risk factors for heart disease (high blood
pressure, high cholesterol, overweight, diabetes, cigarette smoking, male older
than 40 years of age, other family members with early heart disease,
postmenopausal female). Talk with healthcare provider.
Use birth control that you can trust to prevent pregnancy while
taking this medicine. |
|
|
| What are the common side effects
of this
medicine? |
|
|
Feeling lightheaded, sleepy, having blurred vision, or a change in
thinking clearly. Avoid driving, doing other tasks or activities that require
you to be alert or have clear vision until you see how this medicine affects
you.
Nausea or vomiting. Small frequent meals, frequent mouth care,
sucking hard candy, or chewing gum may help.
Nasal irritation.
Abnormal taste. This is usually
reversible. |
|
|
| What should I monitor? |
|
|
Change in condition being treated. Is it better, worse, or about the
same?
Follow up with healthcare provider. |
|
|
| Reasons to call healthcare
provider
immediately |
|
|
If you suspect an overdose, call your local poison control center
immediately or dial 911.
Signs of a life-threatening reaction. These include wheezing; chest
tightness; fever; itching; bad cough; blue skin color; fits; or swelling of
face, lips, tongue, or throat.
Change in strength on one side greater than the other, difficulty
speaking or thinking, change in balance, or blurred vision.
Chest pain or pressure or fast heartbeat.
Numbness or tingling of hands or feet.
Severe dizziness or passing out.
Difficulty breathing.
Severe muscle pain or weakness.
Any rash.
No improvement in condition or feeling
worse. |
|
|
| How should I store this
medicine? |
|
|
Store at room temperature. Do not freeze.
Once the nasal spray is prepared, throw away any unused portion of
the opened ampul after 8 hours.
Protect injectable from light. |
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|
| General statements |
|
|
Do not share your medicine with others and do not take anyone else's
medicine.
Keep all medicine out of the reach of children and pets.
Keep a list of all your medicines (prescription, natural products,
supplements, vitamins, over-the-counter) with you. Give this list to healthcare
provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
Talk with healthcare provider before starting any new medicine,
including over-the-counter, natural products, or
vitamins. |
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