Drugs >  Dornase Alfa
Dornase Alfa
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(DOOR nase AL fa)

Brand Names
Pulmozyme®

Therapeutic Categories
Enzyme

Reasons not to take this medicine
  • Do not give this medicine to a child younger than 5 years of age.
  • If you have an allergy to dornase alfa or any other part of this medicine.
  • If you are allergic to hamster products, talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

  • What is this medicine used for?
  • This medicine is used to decrease the number of lung infections and improve lung function in cystic fibrosis.

  • How does it work?
  • Dornase alfa is an enzyme that works to thin lung secretions.
  • It improves the lungs and the risk of infection may be decreased.

  • How is it best taken?
  • To gain the most benefit, do not miss doses.
  • Take this medicine at a similar time of day.
  • Follow directions given by healthcare provider.
  • For inhaling (puffing) only by an inhaler or as a liquid (solution) through a special machine (nebulizer) into the lungs.
  • Your healthcare provider will teach you to use the nebulizer.
  • Do not mix with any other liquid medicines.

  • What do I do if I miss a dose?
  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop medicine. Talk with healthcare provider.

  • What are the precautions when taking this medicine?
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.

  • What are the common side effects of this medicine?
  • Chest pain or pressure.
  • Change in voice.
  • Nasal congestion.

  • What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?

  • Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Any rash.
  • No improvement in condition or feeling worse.

  • How should I store this medicine?
  • Store in a refrigerator.
  • Protect from light.
  • Store in protective foil pouch until ready for use.
  • Use right after opening.
  • Do not use if solution changes color.
  • Throw away unopened medicine if left at room temperature for more than 24 hours.

  • General statements
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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