Drugs >  Drotrecogin Alfa
Drotrecogin Alfa
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(dro TRE coe jin AL fa)

Brand Names
Xigris®

Therapeutic Categories
Protein C (Activated)

Reasons not to take this medicine
  • If you have an allergy to drotrecogin alfa or any other part of this medicine.
  • If you are allergic to protein C, talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have any of the following conditions: Bleeding problems, blow to the head within the last 2 months, brain tumor, catheter in spine, herniated brain, or stroke within the last 3 months.

  • What is this medicine used for?
  • This medicine is used to treat a severe infection. You may be reading this leaflet for a family member.

  • How does it work?
  • Drotrecogin alfa decreases the body's harmful response to diseases affecting the immune system.

  • How is it best taken?
  • This medicine is given as a shot into a vein.
  • It will be stopped for 2 hours before any procedures where bleeding would be expected.

  • What are the precautions when taking this medicine?
  • If you have liver disease, talk with healthcare provider.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.

  • What are the common side effects of this medicine?
  • Bleeding problems.

  • What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • You will be monitored closely by healthcare provider.

  • Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Unusual bruising or bleeding.
  • No improvement in condition or feeling worse.

  • How should I store this medicine?
  • This medicine will be given to you in a healthcare setting. You will not store it at home.

  • General statements
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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