Drugs >  Fluoxetine
Fluoxetine
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(floo OKS e teen)

Brand Names
Prozac®; Prozac® Weekly™; Sarafem™

Foreign Brand Names
Fluoxac (Mexico)

Therapeutic Categories
Antidepressant, Selective Serotonin Reuptake Inhibitor

Reasons not to take this medicine

  • If you have an allergy to fluoxetine or any other part of the medicine.
  • If you have taken a monoamine oxidase inhibitor (isocarboxazid, phenelzine, tranylcypromine) in the last 14 days.
  • If you are taking thioridazine.


What is this medicine used for?

  • This medicine is used for depression, eating disorders, premenstrual mood disorder(premenstrual dysphoric disorder), and impulse control disorder.
  • Other uses include treatment of alcoholism, attention deficit hyperactivity disorders, anxiety disorders, and some sleep disorders.
  • It is used to treat geriatric depression in patients at least 65 years of age.


How does it work?

  • Fluoxetine increases activity of a chemical in the brain called serotonin. In depression, sleep and appetite may improve quickly. Other symptoms may take up to 4-6 weeks to improve.
  • The increase in serotonin is likely associated with improvements in all the conditions fluoxetine treats.


How is it best taken?

  • To gain the most benefit, do not miss doses.
  • Take in the morning or follow healthcare provider's directions.
  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • A liquid (solution) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not change dose or stop taking medicine without talking with healthcare provider.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Do not use if you are taking thioridazine. May cause dangerous problems.
  • If you are 65 or older, you may have anxiety, be unable to sleep, or not feel hungry.
  • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
  • Avoid alcohol (includes wine, beer, and liquor) and other medicines and herbs that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
  • Separate monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) from this medicine. Do not take together.
  • You can get sunburned more easily. Avoid lots of sun. Use sunscreen; wear protective clothing and eyewear.
  • Tell healthcare provider if you are taking any herbal products.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Nausea or dry mouth. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Feeling tired, weak, or dizzy. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Lack of appetite.
  • Inability to sleep. Take in the morning.
  • Anxiety or nervousness.
  • Headache. Mild pain medicine may help.
  • Change in sexual ability or desire. This can return to normal after medicine is stopped. Talk with healthcare provider about other medicines without this side effect.


What should I monitor?

  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Very nervous and excitable.
  • No improvement in condition or feeling worse after 4-6 weeks of treatment.


How should I store this medicine?

  • Store capsules or tablets at room temperature.
  • Store liquid (solution) in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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