Drugs >  Glipizide and Metformin
Glipizide and Metformin
Pronunciation
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(GLIP i zide & met FOR min)

Brand Names
Metaglip™

Therapeutic Categories
Antidiabetic Agent, Biguanide; Antidiabetic Agent, Sulfonylurea

What key warnings should I know about before taking this medicine?

A small number of people may develop an acidity to their blood. Metformin can cause this. It may occur in people whose liver or kidneys do not work normally.


Reasons not to take this medicine
  • If you have an allergy to glipizide, metformin, or any other part of this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have any of the following conditions: Drink alcohol to excess, dehydration, kidney disease, liver disease, recent heart attack, or severely weakened heart.
  • If you are having an x-ray with dye.

  • What is this medicine used for?
  • This medicine is used to lower blood sugar in diabetic patients.

  • How does it work?
  • Glipizide increases insulin secretion from the pancreas and may make tissues more responsive to insulin.
  • Metformin reduces sugar production and helps insulin work better.

  • How is it best taken?
  • This medicine can be used alone or in combination with other diabetes medicine.
  • Take this medicine with food.
  • Follow diet plan and exercise program as recommended by healthcare provider.

  • What do I do if I miss a dose?
  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop medicine. Talk with healthcare provider.

  • What are the precautions when taking this medicine?
  • Wear disease medical alert identification.
  • Use caution if you are having surgery, if you have a heart attack, severe infection, or stroke, or if you are 80 years of age or older and have not had your kidney function tested.
  • If you have lung disease, talk with healthcare provider.
  • If you have a weakened heart, talk with healthcare provider.
  • Do not drive if blood sugar has been low. There is a greater risk of an accident.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Avoid alcohol (includes wine, beer, and liquor).
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.

  • What are the common side effects of this medicine?
  • Low blood sugar. Signs include anger, shaking, fast heartbeat, confusion, or sweating. Keep hard candies, liquid glucose, or milk on hand for low blood sugar.
  • Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
  • Headache. Mild pain medicine may help.
  • Belly pain.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea.

  • What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • Check blood sugar as directed by healthcare provider.
  • Check blood work (kidney and liver function). Talk with healthcare provider.
  • Have a yearly eye exam and visit to the foot doctor.

  • Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Very low blood sugar or very high blood sugar.
  • Difficulty breathing.
  • Severe dizziness.
  • Severe nausea or vomiting.
  • Severe diarrhea.
  • Severe muscle pain or weakness.
  • Feeling cold.
  • Feeling extremely tired or weak.
  • Any rash.
  • No improvement in condition or feeling worse.

  • How should I store this medicine?
  • Store at room temperature.
  • Protect from moisture. Do not store in a bathroom or kitchen.

  • General statements
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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