Drugs >  Glyburide
Glyburide
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(GLYE byoor ide)

Brand Names
Diabeta®; Glynase™ PresTab™; Micronase®

Foreign Brand Names
Albert® Glyburide (Canada); Apo-Glyburide® (Canada); Daonil (Mexico); Euglucon® (Canada); Euglucon® (Mexico); Gen-Glybe (Canada); Glibenil (Mexico); Glucal (Mexico); Norboral (Mexico); Novo-Glyburide (Canada); Nu-Glyburide (Canada)

Therapeutic Categories
Antidiabetic Agent (Sulfonylurea)

Reasons not to take this medicine

  • If you have an allergy to a sulfonamide, glyburide, or any other part of the medicine.
  • If you have type 1 diabetes or a history of diabetic ketoacidosis.


What is this medicine used for?

  • This medicine is used to lower blood sugar in diabetic patients. It is used in type 2 diabetes. It can be used alone or in combination with other diabetes medicine.
  • May be used instead of insulin in pregnant women to control blood sugars.


How does it work?

  • Glyburide increases insulin secretion from the pancreas. This organ produces insulin. Glyburide makes tissues more sensitive to insulin. This means better blood sugar control.


How is it best taken?

  • Take with first meal of the day.
  • Follow diet plan and exercise program as recommended by healthcare provider.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Wear disease medical alert identification for diabetes.
  • If you are 80 years of age or older, you may be more sensitive to low blood sugars.
  • Avoid alcohol intake (includes wine, beer, and liquor).
  • Keep hard candies, liquid glucose, or milk on hand for low blood sugars.
  • Do not drive if blood sugar has been low. There is a greater risk of an accident.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Low blood sugar. This can cause anger, shaking, rapid heartbeats, confusion, sweating. Can be life-threatening if not treated with hard candies, liquid glucose, milk.
  • Nausea. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.


What should I monitor?

  • Check blood sugar as ordered by healthcare provider. Call if glucose is less than 80 mg/dL or greater than 250 mg/dL. Bring results to follow-up visits.
  • Watch for low blood sugar. This can cause anger, shaking, rapid heartbeats, confusion, sweating.
  • Watch for high blood sugar. Causes many trips to the bathroom, thirst, and weight loss.
  • Check blood work. Talk with healthcare provider.
  • Follow diet plan and exercise program as recommended by healthcare provider.
  • Have a yearly eye exam and visit to the foot doctor.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Any signs or symptoms of infection. This may include a fever greater than 99 degrees, chills, sore throat, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, anal itching or pain.
  • Low blood sugar or very high blood sugar.
  • Any rash.


How should I store this medicine?

  • Store in a tight container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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