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| Pronunciation |
|
 (in
DIN a
veer) |
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| Brand Names |
|
| Crixivan® |
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|
| Therapeutic
Categories |
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|
Antiretroviral Agent, Protease Inhibitor |
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| What key warnings should I know
about before taking this
medicine? |
|
|
- This medicine has been shown to increase the risk of kidney stones.
Be sure to drink enough fluids while taking this medication. Children are more
likely to get kidney stones than
adults.
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| Reasons not to take this
medicine |
|
|
- If you have an allergy to indinavir or any other part of the medicine.
- If you are taking terfenadine, astemizole, cisapride, lovastatin,
simvastatin, triazolam, or
midazolam.
|
|
|
| What is this medicine used
for? |
|
|
- This medicine is used to treat HIV infection. It is usually taken with
2 other medicines.
|
|
|
| How does it work? |
|
|
- Indinavir stops the HIV virus from increasing. It binds up an enzyme
that is needed for reproduction of the
virus.
|
|
|
| How is it best taken? |
|
|
- The medicine must be taken exactly as directed.
- It can be taken with water, juice, skim milk, coffee, or tea. Take 1
hour before or 2 hours after meals.
- Drink 7 tall glasses of liquid everyday unless told to drink less
liquid by healthcare provider. This medicine can cause kidney stones.
- Take around-the-clock (every 8 hours).
- Do not take didanosine (DDI) within 1 hour of this
medicine.
|
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|
| What do I do if I miss a
dose? |
|
|
- Skip a missed dose.
- Return to your regular schedule for the next dose.
- Do not take a double dose or extra doses.
- Do not change dose or stop taking medicine without talking with
healthcare provider.
|
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|
| What are the precautions when
taking this
medicine? |
|
|
- Check medicines with healthcare provider. This medicine may not mix
well with other medicines.
- Do not take with St. John's wort.
- Do not take with cholesterol lowering agents like atorvastatin,
cerivastatin, lovastatin, or simvastatin.
- Do not run out of this medication. Get it refilled today!
- Tell healthcare provider if you are allergic to any medicine. Make
sure to tell about the allergy and how it affected you. This includes telling
about rash; hives; itching; shortness of breath; wheezing; cough; swelling of
face, lips, tongue, throat; or any other symptoms involved.
- Protect against sexual spread of disease. Use an effective method of
birth control. Talk with healthcare provider if you have questions.
- Do not use in pregnancy and do not get pregnant. Use birth control
that you can trust while taking this medicine.
- Breast-feeding is not recommended in HIV
disease.
|
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|
| What are the common side effects
of this
medicine? |
|
|
- Nausea or vomiting. Small frequent meals, frequent mouth care, sucking
hard candy, or chewing gum may help.
- Belly pain and cramps.
- Headache. Mild pain medicine may help.
- Diarrhea.
- Feeling sleepy, tired, or unable to think clearly. Use caution when
driving doing other tasks or activities.
- Kidney stones. Most commonly seen in
children.
|
|
|
| What should I monitor? |
|
|
- Check blood work. Talk with healthcare provider.
- Follow up with healthcare
provider.
|
|
|
| Reasons to call healthcare
provider
immediately |
|
|
- Signs of a life-threatening reaction. These include wheezing;
tightness in the chest; fever; itching; bad cough; blue skin color; fits;
swelling of face, lips, tongue, or throat.
- Severe nausea, vomiting, and/or diarrhea.
- Back pain, blood in urine, fever/chills.
- Any rash.
- No improvement in condition or feeling
worse.
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| How should I store this
medicine? |
|
|
- Store in the original container. Do not take anti-moisture cube out.
- Protect from moisture.
|
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| General statements |
|
|
- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine,
including over-the-counter or natural products (herbs,
vitamins).
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