Drugs >  Interferon Alfa-2a
Interferon Alfa-2a
Pronunciation
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(in ter FEER on AL fa too aye)

Brand Names
Roferon-A®

Therapeutic Categories
Interferon

What key warnings should I know about before taking this medicine?

Alpha interferons may cause or worsen diseases of the mind. Suicide, ideas of suicide or homicide, depression, aggressive behavior, hallucinations, psychoses, and relapse of drug addiction have occurred with use. Alpha interferons may cause or worsen infections and certain autoimmune diseases. If you suspect any of these problems, call healthcare provider right away. Side effects such as low blood pressure, fast heartbeats, and heart attacks have occurred while taking alpha interferons. In patients with severe or worsening signs and symptoms of these conditions, the medicine should be stopped. Problems are usually corrected after you stop the medicine.


Reasons not to take this medicine
  • If you have an allergy to interferon alfa-2a or any other part of this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have any of the following conditions: Liver disease, low platelet count, or low white blood cell count, or severe depression.
  • If you have an autoimmune disease.
  • If you have had a transplant.
  • If you are breast-feeding.

  • What is this medicine used for?
  • This medicine is used to treat a variety of cancers.
  • This medicine is used to treat hepatitis C infection.

  • How does it work?
  • Interferon alfa-2a helps the body's immune system fight viral infections.
  • It may affect the cancer cells or the body's response to the cancer.

  • How is it best taken?
  • To gain the most benefit, do not miss doses.
  • This medicine is given as a shot.
  • Your healthcare provider may teach you how to give the shot.
  • Take this medicine at bedtime to help with flu-like symptoms.
  • Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
  • Throw away needles in needle/sharp disposal box and return box to healthcare provider when full.

  • What do I do if I miss a dose?
  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose, brand, or stop medicine. Talk with healthcare provider.

  • What are the precautions when taking this medicine?
  • If you have drug or alcohol addiction, talk with healthcare provider.
  • If you have heart disease, talk with healthcare provider. The flu-like side effects of interferon may be stressful to heart patients.
  • If you have kidney disease, talk with healthcare provider.
  • If you have lung disease, talk with healthcare provider.
  • If you have thyroid disease, talk with healthcare provider.
  • If you have uncontrolled diabetes, talk with healthcare provider.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
  • Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions. These include sedatives, tranquilizers, mood stabilizers, antihistamines, or pain medicine.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.

  • What are the common side effects of this medicine?
  • Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.
  • Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
  • Headache. Mild pain medicine may help.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea.
  • Not hungry.
  • Hair loss. Hair usually grows back when medicine is stopped.
  • Inability to sleep.

  • What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • If you are diabetic, you will need to monitor blood sugars closely.
  • Check blood work regularly. Talk with healthcare provider.
  • Check weight weekly. Report a weight loss to healthcare provider.
  • Follow up with healthcare provider.

  • Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.
  • Chest pain or pressure or fast heartbeat.
  • Difficulty breathing.
  • Severe belly pain or bloody diarrhea.
  • Severe nausea or vomiting.
  • Unusual bruising or bleeding.
  • Feeling extremely tired or weak.
  • Sudden change in vision, eye pain or irritation.
  • Any rash.
  • No improvement in condition or feeling worse.

  • How should I store this medicine?
  • Store unopened vials in a refrigerator. Do not freeze.

  • General statements
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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