Drugs >  Itraconazole
Itraconazole
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(i tra KOE na zole)

Brand Names
Sporanox®

Foreign Brand Names
Isox (Mexico); Itranax® (Mexico)

Therapeutic Categories
Antifungal Agent, Oral

What key warnings should I know about before taking this medicine?

  • This medicine does not mix well with many medications. It should not be taken if you are also taking terfenadine, astemizole, and cisapride. Life-threatening reactions may occur. Check all medicines with healthcare provider.


Reasons not to take this medicine

  • If you have an allergy to another azole fungus medicine, itraconazole, or any other part of the medicine.
  • If you are taking any of these medicines: Astemizole, cisapride, lovastatin, midazolam, simvastatin, or triazolam.


What is this medicine used for?

  • This medicine is used for the treatment of certain types of fungus (yeast) infections. It can treat oral, esophageal (swallowing tube) infections and fingernail infections too.
  • Sometimes it is used to prevent fungus (yeast) infections.


How does it work?

  • Itraconazole causes a leakiness in the fungus (yeast) cell that causes its death.


How is it best taken?

  • To gain the most benefit, do not miss doses.
  • Take capsule with a full meal.
  • Do not take antacids or sucralfate within 2 hours of this medicine.
  • A liquid (solution) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
  • Take liquid (solution) on an empty stomach. Take 1 hour before or 2 hours after meals.
  • Use entire prescription as directed, even if feeling better.
  • Avoid grapefruit and grapefruit juice.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Avoid alcohol (includes wine, beer, and liquor). Can make infection more difficult to treat.
  • Limit caffeine (for example, tea, coffee, cola) and chocolate intake. Use with this medicine may cause nervousness, shakiness, rapid heartbeats, and anxiety.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Belly pain and cramps.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea. Call healthcare provider if severe or prolonged.
  • Headache. Mild pain medicine may help.
  • Rash. Talk with healthcare provider if one develops.


What should I monitor?

  • Watch for change in temperature or worsening of infection.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Fever and/or chills, nausea, vomiting, belly pain, feeling tired, dark urine, yellow eyes/skin, no appetite.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight light-resistant container at room temperature. Protect capsules from moisture.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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