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| Pronunciation |
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 (kee
toe KOE na
zole) |
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| Brand Names |
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| Nizoral®; Nizoral® A-D Shampoo
[OTC] |
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| Foreign Brand
Names |
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| Akorazol (Mexico) |
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| Therapeutic
Categories |
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Antifungal Agent, Oral; Antifungal Agent, Topical |
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| What key warnings should I know
about before taking this
medicine? |
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|
- This medicine does not mix well with many medications. It should
not be taken if you are also taking terfenadine, astemizole, and cisapride.
Life-threatening reactions may occur. Check all medicines with healthcare
provider. This medicine may (rarely) cause severe liver
damage.
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| Reasons not to take this
medicine |
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|
- If you have an allergy to another azole fungus medicine, ketoconazole,
or any other part of the medicine.
- If you have fungal infections of the brain.
- If you are taking any of these medicines: Terfenadine, astemizole, or
cisapride.
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| What is this medicine used
for? |
|
|
- This medicine is used for the treatment of certain types of fungal
infections.
- Sometimes it is used to prevent fungal infections.
- The shampoo is used to treat
dandruff.
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| How does it work? |
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- Ketoconazole causes a leakiness in the fungal cell that causes its
death.
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| How is it best taken? |
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- Oral:
- To gain the most benefit, do not miss doses.
- Take with food. Take at a similar time every day.
- Do not take antacids or sucralfate within 2 hours of this medicine.
- A liquid (suspension) is available if you cannot swallow pills. Those
who have feeding tubes can also use the liquid. Flush the feeding tube before
and after medicine is given. Shake well first.
- Use entire prescription as directed, even if feeling better.
- Skin, cream:
- Do not take by mouth. For skin only. Keep out of mouth, nose, and eyes
(may burn).
- Wash your hands before and after use.
- Clean affected area before use.
- Use a small amount over the area affected as a light film. Rub in
gently.
- Skin, shampoo:
- Keep out of eyes.
- Wet hair and scalp.
- Apply enough shampoo to lather.
- Lather well and leave on for 1 minute.
- Rinse and reapply, lather and leave on for 3 minutes.
- Rinse and dry hair.
- Shampoo twice a week with 3 days between
shampooing.
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| What do I do if I miss a
dose? |
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- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to
your regular schedule.
- Do not take a double dose or extra
doses.
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| What are the precautions when
taking this
medicine? |
|
|
- Oral:
- Check medicines with healthcare provider. This medicine may not mix
well with other medicines.
- Avoid alcohol (includes wine, beer, and liquor). Can make infection
more difficult to treat.
- Limit caffeine (for example, tea, coffee, cola) and chocolate intake.
Use with this medicine may cause nervousness, shakiness, rapid heartbeats, and
anxiety.
- All forms:
- Tell healthcare provider if you are allergic to any medicine. Make
sure to tell about the allergy and how it affected you. This includes telling
about rash; hives; itching; shortness of breath; wheezing; cough; swelling of
face, lips, tongue, throat; or any other symptoms involved.
- Tell healthcare provider if you are pregnant or plan on getting
pregnant.
- Tell healthcare provider if you are
breast-feeding.
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| What are the common side effects
of this
medicine? |
|
|
- Oral:
- Belly pain and cramps.
- Nausea or vomiting. Small frequent meals, frequent mouth care, sucking
hard candy, or chewing gum may help.
- Diarrhea.
- Headache. Mild pain medicine may help.
- Rash. Talk with healthcare provider if one develops.
- Shampoo:
- Removal of the curl from wavey hair.
- Increase in hair loss.
- Irritation.
- Cream:
- Severe irritation, itching, and
stinging.
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| What should I monitor? |
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- Watch for change in temperature or worsening of
infection.
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| Reasons to call healthcare
provider
immediately |
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- Signs of a life-threatening reaction. These include wheezing;
tightness in the chest; fever; itching; bad cough; blue skin color; fits;
swelling of face, lips, tongue, or throat.
- Fever and/or chills, nausea, vomiting, belly pain, feeling tired, dark
urine, yellow eyes/skin, no appetite.
- Increased irritation of skin or scalp.
- Any rash.
- No improvement in condition or feeling
worse.
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| How should I store this
medicine? |
|
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- Store liquid (suspension) at room temperature. Throw away unused
portion after 60 days.
- Store tablets, cream, and shampoo in a tight container at room
temperature.
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| General statements |
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- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine,
including over-the-counter or natural products (herbs,
vitamins).
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