Drugs >  Metformin
Metformin
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(met FOR min)

Brand Names
Glucophage®; Glucophage® XR

Foreign Brand Names
Glucophage® Forte (Mexico); Novo-Metformin (Canada)

Therapeutic Categories
Antidiabetic Agent (Biguanide)

What key warnings should I know about before taking this medicine?

  • A small number of people may develop an acidity to their blood. Metformin can cause this lactic acidosis. Lactic acidosis is a build up of acid in the blood. It may occur in people whose kidneys or livers do not work normally. If lactic acidosis does occur it can cause death.


Reasons not to take this medicine

  • If you have an allergy to metformin or any other part of the medicine.
  • If you have any of the following conditions: Kidney disease, an acidic condition of the blood, having an x-ray with dye.


What is this medicine used for?

  • This medicine is used to lower blood sugar in diabetic patients. It is used in type 2 diabetes. It can be used alone or in combination with other diabetes medicine. It may take 1 month to see the full effects.
  • It can be used to treat diabetes in children 10 to 16 years of age. The extended release form is only for patients 17 and older.


How does it work?

  • Metformin decreases sugar production in the body and makes insulin work better.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • Swallow extended release (XR) form whole. Do not chew, break, or crush.
  • Follow diet plan and exercise program as recommended by healthcare provider.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Wear disease medical alert identification for diabetes.
  • Avoid alcohol intake (includes wine, beer, and liquor). Can cause side effects.
  • Use caution if you have heart or lung disease. Talk with healthcare provider.
  • You should not take if you have kidney or liver problems, if you have congestive heart failure, if you drink alcohol to excess, if you have lost a large amount of fluid (are dehydrated), if you are getting x-rays with shots of dye in your veins or arteries, if you are going for surgery, is you develop a condition such as a heart attack, severe infection, or stroke, or if you are 80 or older and have not had your kidney function tested.
  • Do not drive if blood sugar has been low. There is a greater risk of an accident.
  • Keep hard candies, liquid glucose, or milk on hand for low blood sugars.
  • If you are 80 years of age or older, you may have more side effects. You may need a low dose.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Belly pain and cramps, gas, not hungry, metal like taste. Dosage decrease may help with all symptoms.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help. Decrease in dose will help.
  • Diarrhea.


What should I monitor?

  • Check blood sugar as ordered by healthcare provider. Call if glucose is less than 80 mg/dL or greater than 250 mg/dL. Bring results to follow-up visits.
  • Watch for low blood sugar. This can cause anger, shaking, rapid heartbeats, confusion, sweating.
  • Watch for high blood sugar. Causes many trips to the bathroom, thirst, and weight loss.
  • Check blood work for diabetes, liver, and kidney function. Talk with healthcare provider.
  • Follow diet plan and exercise program as recommended by healthcare provider.
  • Have a yearly eye exam and visit to the foot doctor.
  • Check weight.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Feeling very weak, tired or uncomfortable.
  • Unusual muscle pain, trouble breathing, stomach pain or discomfort, feeling cold, dizzy or lightheaded.
  • Suddenly developing a slow or irregular heartbeat.
  • Severe nausea, vomiting, fever, and/or diarrhea.
  • Any signs or symptoms of infection. This may include a fever greater than 99 degrees, chills, sore throat, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, anal itching or pain.
  • Low blood sugar or very high blood sugar.
  • Any rash.


How should I store this medicine?

  • Store in a tight container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


Copyright © 1978-2001 Lexi-Comp Inc. All Rights Reserved

 

 

RELATED INFORMATION
  Substances depleted by this drug
View Depletions
  Interactions with supplements
Calcium
Chromium
Fiber
Psyllium
Vitamin B12 (Cobalamin)
Vitamin B3 (Niacin)
Vitamin B9 (Folic Acid)
  Related Articles
View Articles