Drugs >  Metoclopramide
Metoclopramide
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(met oh kloe PRA mide)

Brand Names
Reglan®

Foreign Brand Names
Apo-Metoclop® (Canada); Carnotprim Primperan® (Mexico); Carnotprim Primperan® Retard (Mexico); Maxeran® (Canada); Meclomid (Mexico); Plasil (Mexico); Pramotil (Mexico)

Therapeutic Categories
Gastrointestinal Agent, Prokinetic

Reasons not to take this medicine

  • If you have an allergy to metoclopramide or any other part of the medicine.
  • If you have any of the following conditions: Blockage of the gastrointestinal tract, hole in the gastrointestinal tract, bleeding in the gastrointestinal tract, seizure history, pheochromocytoma.


What is this medicine used for?

  • This medicine is used for the treatment of nighttime heartburn due to gastroesophageal reflux in patients who do not respond to lifestyle changes, antacids, and gastric acid reducing medicine. Lifestyle changes include avoiding alcohol, quitting smoking, elevating the head of the bed, avoiding large meals before bed, losing weight, avoiding fatty foods, chocolate, caffeine, or citrus.
  • It can also be used in patients receiving tube feedings who have high residuals, and in patients with gastroparesis, refractory constipation, and nonulcer dyspepsia.


How does it work?

  • Metoclopramide increases gastric emptying of solid and liquid food and decreases symptoms of nausea, vomiting, heartburn, and fullness.


How is it best taken?

  • Take 15-30 minutes before meals and at bedtime.
  • A liquid (solution, syrup) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible if it is within 1 hour of missing it.
  • Otherwise, skip the missed one and return to your regular schedule.
  • Do not take a double dose or extra doses. This can be very dangerous.


What are the precautions when taking this medicine?

  • Avoid alcohol (includes wine, beer, and liquor). The medicine increases alcohol's effect.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Belly pain and cramps.
  • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
  • Diarrhea.
  • Headache. Mild pain medicine may help.


What should I monitor?

  • Reflux symptoms. If not improved talk, with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Passing out, fainting, dizziness, lightheadedness, or irregular heartbeat (pulse).


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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