Drugs >  Neomycin, Polymyxin B, and ...
Neomycin, Polymyxin B, and Prednisolone
Pronunciation
Brand Names
Therapeutic Categories
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(nee oh MYE sin, pol i MIKS in bee, & pred NIS oh lone)

Brand Names
Poly-Pred® Ophthalmic Suspension

Therapeutic Categories
Antibiotic/Corticosteroid, Ophthalmic

What is this medicine used for?

  • Neomycin and polymixin B are antibiotics used to treat a variety of bacterial infections.
  • Prednisolone is used to reduce redness, irritation, swelling, and itching.
  • The eye drops are used in steroid-responsive inflammatory eye conditions in which hydrocortisone is indicated and where bacterial infection or a risk of bacterial infection exists.


How does it work?

  • Neomycin inhibits metabolic activities in the bacteria.
  • Polymixin B makes some of the manufacturing cells in the bacteria leaky.
  • Prednisolone prevents/reduces irritation and swelling.


How is it best taken?

  • For the eye only.
  • Take out soft contact lenses before using medicine. Lenses can be replaced 15 minutes after medicine is given.
  • After using medicine keep your eyes closed. Apply pressure to the inside corner of the eye. Do this for 3-5 minutes. This keeps medicine in the eye.
  • Separate each eye medicine by 5 minutes. Give one and wait 5 minutes before using the next.
  • Do not touch the bottle tip to eye, lid, or other skin.
  • Use entire prescription as directed, even if feeling better.


What do I do if I miss a dose?

  • Instill a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not instill a double dose or extra doses.


What are the precautions when taking this medicine?

  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Bright lights may be irritating. Keep sunglasses with you.
  • Blurred vision. Use caution when driving, or doing tasks that need clear vision.
  • Stinging after putting drops in eye.


What should I monitor?

  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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