Drugs >  Phenytoin
Phenytoin
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(FEN i toyn)

Brand Names
Dilantin®

Foreign Brand Names
Tremytoine® (Canada)

Therapeutic Categories
Antiarrhythmic Agent, Class I-B; Anticonvulsant, Hydantoin

Reasons not to take this medicine

  • If you have an allergy to phenytoin, other hydantoins, or any other part of the medicine.


What is this medicine used for?

  • This medicine is commonly used to prevent or reduce the number of seizures a person has.
  • It is also used for the treatment of migraine headaches, trigeminal neuralgia, or other neuropathies.


How does it work?

  • Phenytoin stabilizes excitable areas in the brain where seizures may start.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • For the sustained-release capsule, swallow whole. Do not chew, break, or crush.
  • For the chewable tablet, chew or crush well. May be mixed with food or liquid.
  • A liquid (suspension) or a chewable (crushable) tablet is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given. Stop tube feeding at least 2 hours before and after medicine is given. If liquid (suspension) is chosen, shake well before use. Chewable tablet may be given through a feeding tube after crushing and mixing with water.
  • If the liquid is given through a feeding tube, do not give at the same time as nutritional liquids. Talk with healthcare provider.
  • If taken once daily, take at a similar time every day.
  • Do not suddenly stop using this medicine if you have been taking it for a long time. Medicine should be slowly decreased. May cause seizures.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Wear disease medical alert identification for seizure disorder.
  • If you are 65 or older, may may have more side effects. You could feel confused, tired, and sleepy.
  • Do not change make or dosage form. Dosage may need adjustment. Talk to healthcare provider.
  • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
  • If you are taking this medicine for seizures, make sure that you follow your state's laws about driving. Talk with healthcare provider.
  • Avoid alcohol (includes wine, beer, and liquor). It changes how the body handles this medicine making it either more or less effective depending on how you drink alcohol.
  • Avoid other depressant medicines (sedatives, tranquilizers, mood stabilizers, pain medicine) that slow your actions and reactions. Talk with healthcare provider.
  • Take good care of your teeth (brushing, flossing).
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine.
  • Birth control pills may not work. Use another form of birth control while taking this medicine.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Feeling sleepy or unable to think clearly. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you. Confusion, being tired, mood changes, or slurred speech can occur too.
  • Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
  • Changes in balance, feeling shaky or unsteady.


What should I monitor?

  • Periodic phenytoin levels (blood work) are required. Talk with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Changes in balance, feeling shaky or unsteady.
  • Changes in thinking clearly and logically.
  • Nausea, vomiting, or muscle aches.
  • Too tired or sleepy.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.
  • Protect capsules from moisture.
  • Do not freeze liquid (suspension).


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


Copyright © 1978-2001 Lexi-Comp Inc. All Rights Reserved

 

 

RELATED INFORMATION
  Substances depleted by this drug
View Depletions
  Interactions with herbs
Ginkgo Biloba
Kava Kava
Milk Thistle
  Interactions with supplements
Calcium
Vitamin B12 (Cobalamin)
Vitamin B2 (Riboflavin)
Vitamin B6 (Pyridoxine)
Vitamin B9 (Folic Acid)
Vitamin D
Vitamin H (Biotin)
Vitamin K