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| Pronunciation |
|
 (proe
JES ter
one) |
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| Brand Names |
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| Crinone™; Progestasert®;
Prometrium® |
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| Foreign Brand
Names |
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| PMS-Progesterone (Canada); Utrogestan
(Mexico) |
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| Therapeutic
Categories |
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|
Progestin |
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| Reasons not to take this
medicine |
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- If you have an allergy to progesterone or any other part of the
medicine.
- If you have any of the following conditions: A history of blood clots,
unexplained vaginal bleeding, breast cancer, bleeding into the brain, severe
liver disease.
- If you have a peanut allergy and are using the capsules. The capsules
contain peanut oil.
- If you are pregnant.
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| What is this medicine used
for? |
|
|
- This medicine is used for the treatment of abnormal uterine bleeding
due to hormonal imbalance or amenorrhea (no period) where no other cause is
found.
- It is also used to prevent excessive growth of the lining cells of the
uterus in women receiving estrogen replacement.
- It is also used to treat endometriosis.
- The vaginal gel is used in in vitro
fertilization.
- It may be used to prevent endometrial changes in post-menopausal women
who receive estrogen therapy.
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| How does it work? |
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- Progestins are produced by the body and are used by the body for
development of milk-producing glands and for maintenance of the menstrual cycle.
It changes the endometrium.
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| How is it best taken? |
|
|
- Take the tablet with or without food. Take with food if this medicine
causes an upset stomach.
- Use gel vaginally. Follow directions on package
insert.
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| What do I do if I miss a
dose? |
|
|
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to
your regular schedule.
- Do not take a double dose or extra
doses.
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| What are the precautions when
taking this
medicine? |
|
|
- Tell healthcare provider if you have had a history of blood clots in
legs, arms, or lungs or a history of a stroke.
- Tell healthcare provider if you have breast or any genital cancers.
- Tell healthcare provider if you are allergic to any medicine. Make
sure to tell about the allergy and how it affected you. This includes telling
about rash; hives; itching; shortness of breath; wheezing; cough; swelling of
face, lips, tongue, throat; or any other symptoms involved.
- Do not use in pregnancy and do not get pregnant. Use birth control
that you can trust during and for 1 month after therapy.
- Tell healthcare provider if you are
breast-feeding.
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| What are the common side effects
of this
medicine? |
|
|
- Oral:
- Headache. Mild pain medicine may help.
- Nausea. Small frequent meals, frequent mouth care, sucking hard candy,
or chewing gum may help.
- Swelling or bloated feeling.
- Changes in vaginal bleeding.
- Breast tenderness.
- Gel:
- Bloating, belly pain and cramps.
- Breast swelling and
tenderness.
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| What should I monitor? |
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- Follow up with healthcare
provider.
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| Reasons to call healthcare
provider
immediately |
|
|
- Signs of a life-threatening reaction. These include wheezing;
tightness in the chest; fever; itching; bad cough; blue skin color; fits;
swelling of face, lips, tongue, or throat.
- Swelling/pain of a leg or arm, sudden shortness of breath, difficulty
breathing, chest pain.
- Menstrual changes. This includes lots of bleeding, spotting, or
bleeding between cycles.
- Depression.
- Any rash.
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| How should I store this
medicine? |
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- Store in a tight container at room
temperature.
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| General statements |
|
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- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine,
including over-the-counter or natural products (herbs,
vitamins).
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