Drugs >  Saquinavir
Saquinavir
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(sa KWIN a veer)

Brand Names
Fortovase®; Invirase®

Therapeutic Categories
Antiretroviral Agent, Protease Inhibitor

Reasons not to take this medicine

  • If you have an allergy to saquinavir or any other part of the medicine.
  • If you have direct sun exposure without the use of sunscreen or protective clothing.
  • If you are taking any of these medicines: Terfenadine, cisapride, astemizole, triazolam, midazolam, ergot medicine, lovastatin, or simvastatin.


What is this medicine used for?

  • This medicine is used to treat HIV infection. It is usually taken with 2 other medicines.


How does it work?

  • Saquinavir stops the HIV virus from increasing. It binds up an enzyme that is needed for reproduction of the virus.


How is it best taken?

  • The medicine must be taken exactly as directed.
  • Take within 2 hours of a high calorie/high fat meal.
  • Avoid grapefruit or grapefruit juice.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • Return to your regular schedule for the next dose.
  • Do not take a double dose or extra doses.
  • Do not change dose, stop taking medicine, or change brands without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Do not run out of this medication. Get it refilled today!
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Protect against sexual spread of disease. Use an effective method of birth control. Talk with healthcare provider if you have questions.
  • Breast-feeding is not recommended in HIV disease.


What are the common side effects of this medicine?

  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea.
  • Belly pain, cramps, gas.
  • Feeling tired. Use caution in driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Headache. Mild pain medicine may help.
  • Your body fat may redistribute to your trunk. Your legs and arms may be thin but your chest, belly, back and face may have more fat.


What should I monitor?

  • Check blood work. Talk with healthcare provider.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe nausea, vomiting, and/or diarrhea.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store Invirase® in a tight container at room temperature.
  • Store Fortovase® in a tight container in the refrigerator. Once at room temperature, Fortovase® is good for 3 months.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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