Drugs >  Sulfamethoxazole and Trimethoprim
Sulfamethoxazole and Trimethoprim
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(sul fa meth OKS a zole & trye METH oh prim)

Brand Names
Bactrim™; Bactrim™ DS; Septra®; Septra® DS; Sulfatrim®; Sulfatrim® DS

Therapeutic Categories
Antibiotic, Sulfonamide Derivative; Antibiotic, Miscellaneous

Reasons not to take this medicine
  • Do not give this medicine to an infant younger than 2 months of age.
  • If you have an allergy to sulfamethoxazole, trimethoprim, or any other part of this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have any of the following conditions: Anemia because of lack of folic acid, liver disease, or porphyria.
  • If you are pregnant or may be pregnant.
  • If you are breast-feeding.

  • What is this medicine used for?
  • This medicine is used to treat a variety of bacterial infections.

  • How does it work?
  • Sulfamethoxazole and trimethoprim works to injure the bacteria and fight the infection.

  • How is it best taken?
  • To gain the most benefit, do not miss doses.
  • Use prescription as directed, even if feeling better.
  • Take this medicine with food.
  • Take this medicine with a full glass of water.
  • Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
  • A liquid (suspension) is available if you cannot swallow pills. Shake well before use. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

  • What do I do if I miss a dose?
  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
  • Do not take a double dose or extra doses.

  • What are the precautions when taking this medicine?
  • If you are taking a blood thinner, you will require more frequent monitoring.
  • If you have kidney disease, talk with healthcare provider.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Avoid alcohol (includes wine, beer, and liquor).
  • You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
  • Be careful if you have G6PD deficiency. Anemia may occur.
  • Use birth control that you can trust to prevent pregnancy while taking this medicine.

  • What are the common side effects of this medicine?
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Not hungry.

  • What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • If you are taking blood thinner, check blood work (prothrombin time/INR). Talk with healthcare provider.

  • Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Severe nausea or vomiting.
  • Any rash.
  • No improvement in condition or feeling worse.

  • How should I store this medicine?
  • Store at room temperature.
  • Protect from light.
  • Protect tablets from moisture. Do not store in a bathroom or kitchen.

  • General statements
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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