Drugs >  Tenecteplase
Tenecteplase
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Brand Names
TNKase™

Therapeutic Categories
False Neurotransmitter

Reasons not to take this medicine

  • If you have an allergy to tenecteplase or any other part of the medicine.
  • If you have any of the following conditions: Any bleeding, history of stroke, surgery on the brain or spine in the last 2 months, injury to the brain or spine in the last 2 months, brain tumor, bleeding disorder, severe high blood pressure that is not controlled, arteriovenous malformations, aneurysm.


What is this medicine used for?

  • This medicine is used to treat heart attacks. It helps to prevent damage to the heart during a heart attack.
  • It may also save your life.


How does it work?

  • Tenecteplase helps the body's own system dissolve the clot in the heart. The blood clot is preventing oxygen and nutrition from getting to that part of the heart.


How is it best taken?

  • It will be given by a shot intravenously.


What do I do if I miss a dose?

  • It is a single dose. It is given once only.


What are the precautions when taking this medicine?

  • If you had a stomach ulcer or any recent bleeding, surgery, or dental procedures. Tell healthcare provider.
  • Use caution if you have high blood pressure especially if uncontrolled. Talk with healthcare provider.
  • Use caution if you have a history of stroke. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant.


What are the common side effects of this medicine?

  • Bleeding is the most common side effect. The nurses will be watching for bleeding.
  • If you notice any nosebleeds, gum bleeding, blood in the urine or stool, or bleeding from any other place tell the nurses.
  • Rarely serious bleeding can occur.


What should I monitor?

  • Chest pain or pressure. Is it better, worse, or about the same?


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
  • Any bleeding.
  • Recurrent chest pain or pressure.
  • Any rash.


How should I store this medicine?

  • You will only receive this medicine in the hospital.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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