Drugs >  Thalidomide
Thalidomide
Pronunciation
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(tha LI doe mide)

Brand Names
Thalomid®

Therapeutic Categories
Immunosuppressant Agent

What key warnings should I know about before taking this medicine?

  • Using this medicine during pregnancy could cause severe life-threatening birth defects. A man OR a woman must use effective birth control to prevent pregnancy while taking this medication (if there is ANY possibility of becoming pregnant or causing pregnancy). Two effective measures to prevent pregnancy are needed. A written explanation of risks must be presented, reviewed, and signed by the patient before they are to receive this medication. If a patient is under 18 years of age, this written warning must be signed by a parent or legal guardian.


Reasons not to take this medicine

  • If you have an allergy to thalidomide or any other part of the medicine.
  • If you have numbness, pain, or tingling in your hands or feet or a peripheral neuropathy.
  • If you are in your childbearing years or are pregnant.


What is this medicine used for?

  • This medicine is used to treat skin symptoms of leprosy.
  • Other uses include treatment of Behçet's syndrome, lupus, graft versus host reactions after bone marrow transplant, and AIDS-related aphthous ulcers.


How does it work?

  • Thalidomide decreases the body's response to diseases affecting the immune system.


How is it best taken?

  • Take on an empty stomach. Take 1 hour before or 2 hours after meals. Swallow whole. Do not chew, break, or crush.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible. If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • This medicine may be habit-forming with long-term use.
  • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
  • Avoid alcohol (includes wine, beer, and liquor) and other medicines and herbs that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
  • If you have numbness, tingling, or pain in hands or feet tell healthcare provider.
  • You can get sunburned more easily. Avoid lots of sun. Use sunscreen; wear protective clothing and eyewear.
  • The risk of cancer is higher after taking this medicine. It may be related to the dose and length of treatment.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • This medicine causes birth defects.
  • Do not use in pregnancy and do not get pregnant. Use birth control that you can trust before beginning treatment, while taking this medicine, and for 6 weeks after treatment is stopped.
  • Women need to use 2 forms of birth control. Birth control pills may not work. Use other forms of birth control while taking this medicine. Talk with healthcare provider.
  • Men need to protect their partner from getting pregnant.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Diarrhea.
  • Headache. Mild pain medicine may help.
  • Rash.
  • Feeling sleepy or lightheaded. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.


What should I monitor?

  • Take a pregnancy test before starting this medicine. The result should be negative.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Fever and/or chills, sore throat, sore mouth, pain with urination, or coughing up sputum.
  • Numbness, tingling, or pain in the hands and feet.
  • Pregnant.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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