Drugs >  Tinzaparin
Tinzaparin
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Brand Names
Innohep®

Therapeutic Categories
Low Molecular Weight Heparin

What key warnings should I know about before taking this medicine?

  • People who have had recent spinal anesthesia, epidurals, or spinal taps are more likely to have bleeding problems when started on this medicine. This bleeding rarely happens but can be severe. Tell your healthcare provider if you have had any spinal procedures. Do not take any other blood-thinner medicines.


Reasons not to take this medicine

  • If you have an allergy to heparin, sulfites, benzyl alcohol, pork, tinzaparin, or any other part of the medicine.
  • If you have serious bleeding problems or a low platelet count due to heparin.


What is this medicine used for?

  • This medicine is used to treat blood clots in the veins. These are called deep-vein thrombosis or DVT. It can also treat parts of clots that have broken off and traveled to the lungs (pulmonary embolism). Tinzaparin is used with a medicine that is taken by mouth called warfarin (Coumadin®). The tinzaparin is stopped when the warfarin starts working fully. Warfarin usually takes about 5-7 days to work.


How does it work?

  • Tinzaparin changes the body's clotting system. It thins the blood to prevent other clots from forming. Your body dissolves the clot or embolism that is already there.


How is it best taken?

  • This medicine is given by needle into the fatty part of the skin. Your healthcare provider may teach you how to give the shot at home.
  • Throw away needles in red box and return box to healthcare provider when full.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible. Try not to miss doses since this is a once-a-day medicine and you need its blood thinning effects each day.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Wear disease medical alert identification for blood thinner.
  • If you have had an epidural or spinal anesthesia recently tell healthcare provider.
  • If you have any problems with bleeding, high blood pressure, an ulcer in the stomach or intestines, a history of a stroke, any recent surgery including dental surgery, liver disease, diabetes with eye problems, talk with healthcare provider.
  • You will have a tendency to bleed more easily. Use caution to prevent injury and avoid falls or accidents. Tell dentists, surgeons, and other healthcare providers about this medicine. Use soft toothbrush, electric razor.
  • Avoid other blood thinners (aspirin, aspirin-containing products, ibuprofen or like products, ticlopidine, clopidogrel, garlic, ginseng, ginkgo, vitamin E) unless approved by healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Bleeding problems. This may include nosebleeds, coughing up blood, blood in the urine or stool, or bruising.
  • If you are female this could also mean vaginal bleeding or heavier bleeding from your monthly period.


What should I monitor?

  • Watch for signs and symptoms of bleeding. These would include bleeding that does not stop from cuts or from your nose, more bleeding than usual when you brush your teeth, unusual colored urine or stool (dark brown or red urine; red or black stool), unusual bruising (black and blue marks on your skin), throwing up or coughing up blood.
  • If you are female, watch for unusual vaginal bleeding or more bleeding than usual during your period.
  • Report any bleeding symptoms to healthcare provider right away.
  • Check blood work. Talk with healthcare provider. Your warfarin therapy will need checking frequently at first and then periodically when you are stable on it.
  • Take good care of your teeth. See a dentist every 6 months.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest, fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
  • Severe headache.
  • Passing out, fainting, dizziness, or lightheadedness.
  • Changes in thinking clearly and logically.
  • Blood in the stool or toilet bowl, vomiting blood, or coughing up blood.
  • Numbness or tingling of the leg, unable to walk or move.
  • Any falls or accidents, especially if you hit your head. Call healthcare provider even if you feel fine.
  • Any rash.
  • Unusual bruising or any bleeding.


How should I store this medicine?

  • Store at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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