Drugs >  Trandolapril and Verapamil
Trandolapril and Verapamil
Pronunciation
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(tran DOE la pril & ver AP a mil)

Brand Names
Tarka®

Therapeutic Categories
Antihypertensive Agent, Combination

What key warnings should I know about before taking this medicine?

  • Do not use this medicine if you are pregnant. Use during the second and third trimester (more than 12 weeks pregnant) can cause harm to the baby you are carrying. Call healthcare provider right away if you become pregnant. Your medicine will need to be changed.


Reasons not to take this medicine

  • If you have an allergy to trandolapril, verapamil, or any other part of the medicine. If you are allergic to another angiotensin converting enzyme inhibitor, talk with healthcare provider.
  • If you have any of the following conditions: Disease of the vessels (arteries) that take blood to the kidney, primary hyperaldosteronism, idiopathic or hereditary angioedema, low blood pressure, weakened heart (congestive heart failure) whose symptoms are poorly controlled, Wolff-Parkinson-White Syndrome, Lown-Ganoang-Levine syndrome, slow heart rate without a pacemaker that works.
  • If you are pregnant.


What is this medicine used for?

  • This medicine is used to treat high blood pressure.


How does it work?

  • Verapamil blocks certain channels in blood vessels that cause a relaxation and a lowering of blood pressure.
  • Trandolapril lowers blood pressure by decreasing production of a strong chemical in the body that increases blood pressure.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • Swallow whole. Do not chew, break, or crush.
  • Take at a similar time every day.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • There should be an interval of 24 hours between doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Wear disease medical alert identification for high blood pressure.
  • Limit alcohol intake (includes wine, beer, and liquor). Can increase blood pressure.
  • Avoid potassium-containing salt substitutes and potassium supplements. Talk with healthcare provider.
  • Do not use over-the-counter products that increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain herbs or supplements. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Lightheaded. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
  • Headache. Mild pain medicine may help.
  • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
  • Abnormal taste (metallic, salty, or none). This is usually reversible.
  • Fluid accumulation usually as ankle swelling.
  • Dry cough.


What should I monitor?

  • Check blood pressure regularly.
  • Follow diet plan (low salt) and exercise program as recommended by healthcare provider.
  • Check blood work. Talk with healthcare provider.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe headache.
  • Passing out, fainting, dizziness, or lightheadedness.
  • Excessive sweating, dehydration, vomiting, or diarrhea. May lead to low blood sugar.
  • Significant, persistent cough.
  • Any rash.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature. Protect from moisture.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your (prescription, herbal/supplements, vitamins, over-the-counter) medicines with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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