Drugs >  Zonisamide
Zonisamide
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(zoe NIS ay mide)

Brand Names
Zonegran®

Therapeutic Categories
Anticonvulsant, Miscellaneous

Reasons not to take this medicine

  • If you have an allergy to a sulfonamide, zonisamide, or any other part of the medicine.


What is this medicine used for?

  • This medicine is used to prevent partial seizures. It is used in combination with other medicines for seizure control.


How does it work?

  • Zonisamide's actions are not exactly known. It does affect the electricity in the brain. This stabilizes the brain and prevents seizures.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • Take with 6 to 8 glasses of water everyday unless told to drink less liquid. This may help prevent kidney stones.
  • Swallow capsule whole. Do not chew, break, or crush.
  • Medicine must be taken exactly as directed.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider. Can cause seizures.


What are the precautions when taking this medicine?

  • Wear disease medical alert identification for seizure disorder.
  • Avoid alcohol (includes wine, beer, and liquor) and other medicines and herbs that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider.
  • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
  • Use caution if you have kidney disease especially if you have had kidney stones. Talk with healthcare provider.
  • Use caution if you have lung disease. This includes asthma, chronic obstructive pulmonary disease, sleep apnea, or if you use an inhaler like albuterol or ipratropium. Can cause wheezing, spasm, or a decreased supply of oxygen to your body. Talk with healthcare provider before using.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Do not take St. John's wort. It may make this medicine less effective.
  • Tell healthcare provider if you are allergic to any medicine especially sulfa drugs (certain antibiotics, diuretics and antidiabetic medicines). Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Feeling sleepy, tired or dizzy. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Loss of appetite.
  • Headache. Mild pain medicine may help.
  • Nausea. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Nervousness and irritability.


What should I monitor?

  • Change in seizure disorder. Is it better, worse, or about the same? May take several weeks to a month to see the full benefits.
  • Periodic blood work for kidney function.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
  • If seizures worsen or occur more often.
  • Back pain, belly pain, or blood in your urine. May be signs of a kidney stone.
  • Fever, chills, sore throat, sores in mouth or easy bruising.
  • Too tired, sleepy, very dizzy, or changes in balance or thinking.
  • Feeling depressed.
  • Any rash.


How should I store this medicine?

  • Store in tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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