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Overview |
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Next to calcium, phosphorus is the most abundant mineral in the body. These
two important nutrients work closely together to build strong bones and teeth.
Approximately 85% of phosphorus in the body can be found in bones and teeth and
roughly 10% circulates in the bloodstream. The remaining phosphorous can be
found in cells and tissues throughout the body. Phosphorous helps filter out
waste in the kidneys and contributes to energy production in the body by
participating in the breakdown of carbohydrates, protein, and fats. It also
helps reduce muscle pain after a hard workout. Phosphorus is needed for the
growth, maintenance, and repair of all tissues and cells, and for the production
of the genetic building blocks, DNA and RNA. Phosphorus is also needed to
balance and metabolize other vitamins and minerals, including vitamin D,
calcium, iodine, magnesium, and zinc.
Phosphorous deficiencies can be caused by excessive intake of aluminum
containing agents (such as certain antacids) because the aluminum can bind to
phosphorous. In addition, diabetes, starvation, alcoholism, and conditions that
can cause abnormal absorption of nutrients (such as Crohn's disease, celiac
disease, and radiation damage) can lead to depletion of phosphorous in the body.
Symptoms of phosphate deficiency include loss of appetite, anxiety, bone pain,
bone fragility, stiffness in the joints, fatigue, irregular breathing,
irritability, numbness, weakness, and weight change. In children, decreased
growth and poor bone and tooth development may occur.
Having too much phosphorous in the body is actually more common and more
worrisome than having too little of this mineral. Excessive phosphorous is
generally caused by kidney disease or by consuming too much dietary phosphorous
relative to dietary calcium. As dietary phosphorous increases, the need for
additional calcium rises as well. The delicate balance between calcium and
phosphorous is necessary for proper bone density and prevention of osteoporosis.
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Uses |
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Because most foods contain sufficient amounts of phosphorus, additional
supplementation with this mineral is not generally necessary. Sometimes athletes
use phosphate supplements before competitions or heavy workouts to help reduce
muscle pain and fatigue. Phosphorus and calcium can be used together to help
heal bone fractures and to treat bone disorders caused by vitamin D
deficiencies, namely osteomalacia and rickets (softening and weakening of the
bones in adults and children respectively). |
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Dietary Sources |
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Protein-rich foods, such as meat, poultry, fish, eggs, dairy products, nuts,
and legumes are particularly good sources of phosphorus. Other sources include
whole grains, hard potatoes, dried fruit, garlic cloves, and carbonated
beverages. |
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Available Forms |
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Elemental phosphorus, a white or yellow waxy substance that burns on contact
with air is highly toxic and no longer used in medicine. (Although, it is used
in some homeopathic treatments and should be taken only under the guidance of a
qualified practitioner). Instead, health care providers may recommend using one
or more of the following inorganic phosphates, which are not toxic:
- Dibasic potassium phosphate
- Monobasic potassium phosphate
- Dibasic sodium phosphate
- Monobasic sodium phosphate
- Tribasic sodium phosphate
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How to Take It |
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Daily recommendations for dietary phosphorous are listed below:
Pediatric
- Infants 0 to 6 months: 100 mg (adequate intake)
- Infants 7 to 12 months: 275 mg (adequate intake)
- Children 1 to 3 years: 460 mg (RDA)
- Children 4 to 8 years: 500 mg (RDA)
- Children 9 to 18 years: 1,250 mg (RDA)
Adult
- 19 years and older: 700 mg (RDA)
- Pregnant and breastfeeding females under 18 years: 1,250 mg (RDA)
- Pregnant and breastfeeding females 19 years and older: 700 mg (RDA)
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Precautions |
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Because of the potential for side effects and interactions with medications,
dietary supplements should be taken only under the supervision of a
knowledgeable healthcare provider.
Too much phosphate can lead to diarrhea and calcification (hardening) of
organs and soft tissue, and can interfere with the body's ability to use iron,
calcium, magnesium, and zinc. Athletes and others taking supplements that
contain phosphate, should only do so very occasionally and with the
guidance/direction of a health care provider.
Nutritionists recommend a balance of calcium and phosphorus in the diet. The
typical Western diet, however, is imbalanced in these minerals. Most people who
consume this type of diet consume roughly two to four times more phosphorus than
calcium. For example, meat and poultry contain 10 to 20 times as much phosphorus
as calcium, and carbonated beverages such as colas have as much as 500 mg of
phosphorus in one serving. When there is more phosphorus than calcium in the
system, the body will draw on calcium stored in bones. This can lead to reduced
bone mass (namely, osteopenia or osteoporosis) that makes bones brittle and
fragile. It can also lead to gum and teeth problems. A balance of dietary
calcium and phosphorus can lower the risk of osteoporosis, and relieve the
symptoms of osteoarthritis and other problems related to the body's ability to
use calcium. |
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Possible Interactions |
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High doses of insulin may decrease blood levels of phosphorus in people with
diabetic ketoacidosis (a condition caused by severe insulin insufficiency). This
serious condition is treated in a hospital and replacement of phosphorous takes
place under the direction of a physician. |
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Supporting Research |
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Anderson JJB. Calcium, phosphorus, and human bone development. J Nutr.
1996;126:1153S–1158S.
Berner YN, Shike M. Consequences of phosphate imbalance. Ann Rev Nutr.
1988;8:121–148.
Carey CF, Lee HH, Woeltje KF, eds. The Washington Manual of Medical
Therapeutics. 29th ed. New York, NY: Lippincott-Raven;
1998:230–237,444–448.
Matsumura M, Nakashima A, Tofuku Y. Electrolyte disorders following massive
insulin overdose in a patient with type 2 diabetes. Intern Med.
2000;39(2):55-57.
Metz JA, Anderson JJB, Gallagher Jr PN. Intakes of calcium, phosphorus, and
protein, and physical activity level are related to radial bone mass in young
adult women. Am J Clin Nutr. 1993;58:
537–542.
Physicians' Desk Reference. 55th ed. Montvale, NJ: Medical Economics
Co., Inc.; 2001:2136-2137.
Reynolds JEF, ed. Martindale: The Extra Pharmacopoeia. 31st ed.
London, Great Britain: Royal Pharmaceutical Society;
1996:1181–1182, 1741.
Villa ML, Packer E, Cheema M, et al. Effects of aluminum hydroxide on the
parathyroid-vitamin D axis of postmenopausal women. J Clin Endocrinol
Metab. 1991;73:1256–1261.
Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: the new basis
for recommendations for calcium and related nutrients, B vitamins, and choline.
J Am Dietetic Assn. 1998;98(6):699-706. |
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Review Date:
April 2002 |
Reviewed By:
Participants in the review process include: Ruth
DeBusk, RD, PhD, Editor,
Nutrition in Complementary Care, Tallahassee, FL; Jacqueline A. Hart, MD,
Department of Internal Medicine, Newton-Wellesley Hospital, Harvard University
and Senior Medical Editor Integrative Medicine, Boston, MA; Gary Kracoff, RPh
(Pediatric Dosing section February 2001), Johnson Drugs, Natick, Ma; Steven
Ottariono, RPh (Pediatric Dosing section February 2001), Veteran's
Administrative Hospital, Londonderry, NH. All interaction sections have also
been reviewed by a team of experts including Joseph Lamb, MD (July 2000), The
Integrative Medicine Works, Alexandria, VA;Enrico Liva, ND, RPh (August 2000),
Vital Nutrients, Middletown, CT; Brian T Sanderoff, PD, BS in Pharmacy (March
2000), Clinical Assistant Professor, University of Maryland School of Pharmacy;
President, Your Prescription for Health, Owings Mills, MD; Ira Zunin, MD, MPH,
MBA (July 2000), President and Chairman, Hawaii State Consortium for Integrative
Medicine, Honolulu, HI.
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