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Pronunciation |
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(per
FEN a
zeen) |
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Brand Names |
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Trilafon® |
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Foreign Brand
Names |
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Apo-Perphenazine® (Canada); Leptopsique
(Mexico); PMS-Perphenazine (Canada) |
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Therapeutic
Categories |
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Antipsychotic Agent, Phenothazine, Piperazine |
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Reasons not to take this
medicine |
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- If you have an allergy to another phenothiazine, perphenazine, or any
other part of the medicine.
- If you have any of the following conditions: Liver disease,
abnormalities in any of the cells in your blood, brain damage, bone marrow
disease.
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What is this medicine used
for? |
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- This medicine is used for the treatment of symptoms seen in
schizophrenia, nausea and vomiting, behavioral problems in patients with mental
retardation.
- Other uses include treatment of Tourette's disorder, behavioral
problems in children, behavior problems of dementia in the elderly, treatment of
disabling involuntary movements in Huntington's chorea, alcohol withdrawal,
spasmodic torticollis, and Reye's syndrome.
- It may take weeks to see the benefits in
schizophrenia.
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How does it work? |
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- Perphenazine changes a variety of chemicals in the
brain.
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How is it best taken? |
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- Take with or without food. Take with food if this medicine causes an
upset stomach.
- A liquid (concentrate) is available if you cannot swallow pills. Those
who have feeding tubes can also use the liquid. Flush the feeding tube before
and after medicine is given. Mix with
1/2
a cup of water before drinking.
- Make sure you are drinking enough liquids unless told to drink less by
healthcare provider. Avoid products with caffeine.
- Do not suddenly stop using this medicine if you have been taking it
for a long time. Medicine should be slowly decreased.
- Do not spill liquid concentrate on skin. Can irritate your
skin.
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What do I do if I miss a
dose? |
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- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed one. Return to
your regular schedule.
- Do not take a double dose or extra
doses.
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What are the precautions when
taking this
medicine? |
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- If you are 65 or older, you may have more side effects.
- You may not be alert. Avoid driving, doing other tasks or activities
until you see how this medicine affects you.
- Avoid alcohol (includes wine, beer, and liquor) and other medicines
and herbs that slow your actions and reactions. This includes sedatives,
tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare
provider.
- Be careful in hot weather. You may be more sensitive to the heat.
- You can get sunburned more easily. Avoid lots of sun. Use sunscreen;
wear protective clothing and eyewear.
- Tell healthcare provider if you are allergic to any medicine. Make
sure to tell about the allergy and how it affected you. This includes telling
about rash; hives; itching; shortness of breath; wheezing; cough; swelling of
face, lips, tongue, throat; or any other symptoms involved.
- Tell healthcare provider if you are pregnant or plan on getting
pregnant.
- Do not use if you are
breast-feeding.
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What are the common side effects
of this
medicine? |
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- Feeling sleepy, lightheaded, or having blurred vision. Avoid driving,
doing other tasks or activities that require you to be alert until you see how
this medicine affects you.
- Dizziness is common. Rise slowly over several minutes from sitting or
lying position. Be careful climbing stairs.
- Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may
help.
- Constipation. More liquids, regular exercise, or a fiber-containing
diet may help. Talk with healthcare provider about a stool softener or laxative.
- Unable to pass urine. Go to the bathroom before taking medicine. Talk
with healthcare provider if it becomes a problem.
- Movements not controlled by you, shakiness, difficulty moving around,
or stiffness.
- Restlessness and inability to stay still or calm.
- Weight gain.
- Change in sexual ability or desire. This can return to normal after
medicine stopped. Talk with healthcare provider about other medicines without
this side effect.
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What should I monitor? |
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- Monitor for side effects.
- Follow up with healthcare
provider.
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Reasons to call healthcare
provider
immediately |
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- Signs of a life-threatening reaction. These include wheezing;
tightness in the chest; fever; itching; bad cough; blue skin color; fits;
swelling of face, lips, tongue, or throat.
- Movements not controlled by you, shakiness, difficulty moving around,
or stiffness.
- Restlessness and inability to stay still or calm.
- Changes in balance, feeling shaky or unsteady.
- Too tired or sleepy.
- Passing out, fainting, dizziness, or lightheadedness.
- Menstrual changes. This includes lots of bleeding, spotting, or
bleeding between cycles.
- Any rash.
- No improvement in condition or feeling
worse.
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How should I store this
medicine? |
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- Store in a tight, light-resistant container at room
temperature.
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General statements |
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- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine,
including over-the-counter or natural products (herbs,
vitamins).
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