There are no known scientific reports of interactions between celery seed and conventional medications. However, given that celery seed is an herb with diuretic effects, people taking prescription diuretics (such as furosemide or hydrochlorothiazide) should not take this herb without first consulting a healthcare provider.

Similarly, celery contains properties that may thin the blood, thus making it somewhat of a concern to take with blood thinning medications such as warfarin or aspirin. If you take warfarin in particular you should not use celery seed without first consulting your healthcare provider.