If you are currently being treated with any of the following medications, you should not use vitamin B5 supplements without first talking to your healthcare provider.

Antibiotics, Tetracycline
Vitamin B5 should not be taken at the same time as the antibiotic tetracycline because it interferes with the absorption and effectiveness of this medication. B vitamins should be taken at different times from tetracycline. (All vitamin B complex supplements act in this way and should therefore be taken at different times from tetracycline.)